Controlling muscle mitochondrial content
نویسندگان
چکیده
منابع مشابه
The effects of apelin treatment on skeletal muscle mitochondrial content.
Adipose tissue is recognized as a key player in the regulation of whole body metabolism. Apelin, is a recently identified adipokine that when given to mice results in increases in skeletal muscle uncoupling protein 3 (UCP3) content. Similarly, acute apelin treatment has been shown to increase the activity of 5'-AMP-activated protein kinase (AMPK), a reputed mediator of skeletal muscle mitochond...
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Dietary restriction (DR) is suggested to induce mitochondrial biogenesis, although recently this has been challenged. Here we determined the impact of 1, 9 and 18 months of 30% DR in male C57BL/6 mice on key mitochondrial factors and on mitochondrial function in skeletal muscle, relative to age-matched ad libitum (AL) controls. We examined proteins and mRNAs associated with mitochondrial biogen...
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ژورنال
عنوان ژورنال: Journal of Experimental Biology
سال: 2003
ISSN: 1477-9145,0022-0949
DOI: 10.1242/jeb.00699